25 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Annual Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Knik-Fairview | 1 | 19,543 | 17,682 | 1.6% | 266 | 74 | CDP |
| North Lakes | 2 | 12,827 | 9,321 | 7.14% | 828 | 15 | CDP |
| Wasilla | 3 | 10,618 | 9,115 | 2.91% | 857 | 12 | City |
| Tanaina | 4 | 10,053 | 10,449 | 1.24% | 332 | 30 | CDP |
| Meadow Lakes | 5 | 9,074 | 8,307 | 1.11% | 120 | 75 | CDP |
| South Lakes | 6 | 8,018 | 6,151 | 7.15% | 1,027 | 8 | CDP |
| Palmer | 7 | 6,797 | 5,939 | 2.58% | 1,340 | 5 | City |
| Gateway | 8 | 6,413 | 5,965 | 0.9% | 349 | 18 | CDP |
| Fishhook | 9 | 5,224 | 4,759 | 0.69% | 80 | 65 | CDP |
| Butte | 10 | 3,878 | 3,888 | 1.09% | 115 | 34 | CDP |
| Big Lake | 11 | 3,202 | 2,769 | -0.31% | 28 | 115 | CDP |
| Farm Loop | 12 | 2,944 | 2,637 | 4.55% | 323 | 9 | CDP |
| Houston | 13 | 2,287 | 1,980 | 2.74% | 96 | 24 | City |
| Point MacKenzie | 14 | 2,002 | 1,323 | 5.2% | 12 | 162 | CDP |
| Willow | 15 | 1,914 | 1,956 | -0.67% | 3 | 690 | CDP |
| Lazy Mountain | 16 | 1,679 | 1,644 | 0.78% | 29 | 59 | CDP |
| Susitna North | 17 | 1,614 | 1,271 | 1.51% | 6 | 276 | CDP |
| Sutton-Alpine | 18 | 1,292 | 1,343 | -0.77% | 22 | 58 | CDP |
| Talkeetna | 19 | 1,086 | 1,199 | 1.31% | 12 | 94 | CDP |
| Buffalo Soapstone | 20 | 985 | 937 | 0.92% | 45 | 22 | CDP |
| Knik River | 21 | 842 | 807 | 0.84% | 10 | 82 | CDP |
| Chickaloon | 22 | 286 | 173 | 0.35% | 4 | 67 | CDP |
| Trapper Creek | 23 | 259 | 304 | -5.13% | 1 | 320 | CDP |
| Glacier View | 24 | 212 | 176 | -0.47% | 1 | 232 | CDP |
| Skwentna | 25 | 79 | 30 | 6.76% | 0.00 | 439 | CDP |
Knik-Fairview is the largest city in Matanuska-Susitna Borough, with a population of 19,543.
Skwentna is the smallest city in Matanuska-Susitna Borough, with a population of 79.
There are 25 cities in Matanuska-Susitna Borough, Alaska.