12 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Annual Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Piggott | 1 | 3,495 | 3,624 | -0.74% | 648 | 5 | City |
| Corning | 2 | 3,052 | 3,221 | -1.1% | 831 | 4 | City |
| Rector | 3 | 1,776 | 1,848 | -0.84% | 1,303 | 1 | City |
| St. Francis | 4 | 207 | 215 | -0.96% | 583 | 0 | City |
| Pollard | 5 | 183 | 193 | -1.08% | 616 | 0 | City |
| Greenway | 6 | 169 | 174 | -0.59% | 650 | 0 | City |
| Knobel | 7 | 144 | 148 | -0.69% | 342 | 0 | City |
| McDougal | 8 | 126 | 131 | -0.79% | 340 | 0 | Town |
| Peach Orchard | 9 | 102 | 105 | -0.97% | 99 | 1 | City |
| Success | 10 | 94 | 98 | -1.05% | 422 | 0 | Town |
| Nimmons | 11 | 64 | 67 | -1.54% | 256 | 0 | Town |
| Datto | 12 | 63 | 66 | -1.56% | 101 | 1 | Town |
Piggott is the largest city in Clay County, with a population of 3,495.
Datto is the smallest city in Clay County, with a population of 63.
There are 12 cities in Clay County, Arkansas.