6 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Annual Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Blountstown | 1 | 2,271 | 2,266 | 0.09% | 713 | 3 | City |
| Blountstown | 2 | 2,271 | 2,261 | 0.09% | 713 | 3 | City |
| Wewahitchka | 3 | 2,216 | 2,072 | 1.28% | 331 | 7 | City |
| Wewahitchka | 4 | 2,216 | 2,076 | 1.28% | 331 | 7 | City |
| Altha | 5 | 496 | 492 | 0.2% | 371 | 1 | Town |
| Altha | 6 | 496 | 491 | 0.2% | 371 | 1 | Town |
Blountstown is the largest city in Calhoun County, with a population of 2,271.
Altha is the smallest city in Calhoun County, with a population of 496.
There are 6 cities in Calhoun County, Florida.