8 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Annual Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Waynesboro | 1 | 5,480 | 5,797 | -1.14% | 1,001 | 5 | City |
| Sardis | 2 | 999 | 998 | 0% | 645 | 2 | City |
| Midville | 3 | 377 | 386 | -0.53% | 189 | 2 | City |
| Keysville | 4 | 311 | 301 | 0.65% | 295 | 1 | City |
| Girard | 5 | 182 | 182 | 0% | 58 | 3 | Town |
| Gough | 6 | 144 | 158 | 7.46% | 171 | 1 | CDP |
| Summertown | 7 | 120 | 119 | 0% | 153 | 1 | City |
| Vidette | 8 | 102 | 102 | 0% | 105 | 1 | City |
Waynesboro is the largest city in Burke County, with a population of 5,480.
Vidette is the smallest city in Burke County, with a population of 102.
There are 8 cities in Burke County, Georgia.