19 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Annual Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Salina | 1 | 45,926 | 46,841 | -0.4% | 1,755 | 26 | City |
| Gypsum | 2 | 10,510 | 10,036 | 1.41% | 303 | 35 | Township |
| Elm Creek | 3 | 863 | 868 | 0.12% | 24 | 35 | Township |
| Smoky View | 4 | 834 | 840 | -0.12% | 23 | 36 | Township |
| Smolan | 5 | 668 | 678 | -0.15% | 21 | 32 | Township |
| Assaria | 6 | 423 | 426 | -0.24% | 1,808 | 0 | City |
| Spring Creek | 7 | 415 | 422 | 0.24% | 6 | 72 | Township |
| Ohio | 8 | 411 | 411 | 0.49% | 11 | 36 | Township |
| Cambria | 9 | 396 | 395 | 0.25% | 11 | 36 | Township |
| Gypsum | 10 | 391 | 404 | -0.76% | 1,045 | 0 | City |
| Pleasant Valley | 11 | 376 | 374 | 0% | 10 | 36 | Township |
| Falun | 12 | 251 | 251 | 0% | 3 | 72 | Township |
| Smoky Hill | 13 | 247 | 251 | 0% | 11 | 22 | Township |
| Brookville | 14 | 233 | 241 | -0.85% | 405 | 1 | City |
| Falun | 15 | 178 | 57 | 7.23% | 161 | 1 | CDP |
| Gypsum | 16 | 172 | 174 | 0% | 5 | 36 | Township |
| Dayton | 17 | 113 | 115 | -0.88% | 3 | 35 | Township |
| New Cambria | 18 | 108 | 105 | 0% | 607 | 0 | City |
| Glendale | 19 | 89 | 89 | 0% | 2 | 36 | Township |
Salina is the largest city in Saline County, with a population of 45,926.
Glendale is the smallest city in Saline County, with a population of 89.
There are 19 cities in Saline County, Kansas.