4 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Annual Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Barbourville | 1 | 3,047 | 3,215 | -1.1% | 1,148 | 3 | City |
| North Corbin | 2 | 2,001 | 1,842 | 0.81% | 1,163 | 2 | CDP |
| Flat Lick | 3 | 864 | 920 | -0.69% | 181 | 5 | CDP |
| Artemus | 4 | 714 | 724 | 1.13% | 529 | 1 | CDP |
Barbourville is the largest city in Knox County, with a population of 3,047.
Artemus is the smallest city in Knox County, with a population of 714.
There are 4 cities in Knox County, Kentucky.