9 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Annual Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Central City | 1 | 5,725 | 5,819 | -0.33% | 1,093 | 5 | City |
| Greenville | 2 | 4,321 | 4,479 | -0.74% | 841 | 5 | City |
| Powderly | 3 | 787 | 786 | 0% | 504 | 2 | City |
| Beechmont | 4 | 762 | 592 | 0.66% | 419 | 2 | CDP |
| Drakesboro | 5 | 471 | 478 | -0.42% | 853 | 1 | City |
| Dunmor | 6 | 261 | 169 | 6.97% | 101 | 3 | CDP |
| Bremen | 7 | 170 | 173 | -0.58% | 821 | 0 | City |
| South Carrollton | 8 | 137 | 139 | -0.72% | 542 | 0 | City |
| Cleaton | 9 | 128 | 163 | 7.56% | 206 | 1 | CDP |
Central City is the largest city in Muhlenberg County, with a population of 5,725.
Cleaton is the smallest city in Muhlenberg County, with a population of 128.
There are 9 cities in Muhlenberg County, Kentucky.