2 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Annual Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Leakesville | 1 | 3,732 | 3,785 | -0.29% | 594 | 6 | Town |
| State Line | 2 | 461 | 448 | 0.44% | 108 | 4 | Town |
Leakesville is the largest city in Greene County, with a population of 3,732.
State Line is the smallest city in Greene County, with a population of 461.
There are 2 cities in Greene County, Mississippi.