3 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Annual Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Picayune | 1 | 12,052 | 11,874 | 0.29% | 668 | 18 | City |
| Poplarville | 2 | 2,919 | 2,814 | 0.72% | 540 | 5 | City |
| Nicholson | 3 | 2,013 | 2,477 | -3.45% | 333 | 6 | CDP |
Picayune is the largest city in Pearl River County, with a population of 12,052.
Nicholson is the smallest city in Pearl River County, with a population of 2,013.
There are 3 cities in Pearl River County, Mississippi.