5 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Tutwiler | 1 | 2,379 | 2,476 | -0.79% | 859 | 2.77 | Town |
| Charleston | 2 | 1,623 | 1,870 | -2.93% | 1,198 | 1.35 | City |
| Webb | 3 | 366 | 410 | -2.4% | 867 | 0.42 | Town |
| Sumner | 4 | 234 | 274 | -3.31% | 425 | 0.55 | Town |
| Glendora | 5 | 132 | 149 | -2.22% | 917 | 0.14 | Village |
Tutwiler is the largest city in Tallahatchie County, with a population of 2,379.
Glendora is the smallest city in Tallahatchie County.
There are 5 cities in Tallahatchie County, Mississippi.