34 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Annual Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Kansas City | 1 | 512,360 | 508,220 | 0.16% | 1,628 | 315 | City |
| Liberty | 2 | 31,172 | 30,227 | 0.61% | 1,051 | 30 | City |
| Gladstone | 3 | 27,475 | 27,109 | 0.27% | 3,400 | 8 | City |
| Liberty | 4 | 14,818 | 14,951 | 0.01% | 99 | 150 | Township |
| Kearney | 5 | 11,458 | 10,462 | 1.77% | 859 | 13 | City |
| Smithville | 6 | 10,986 | 10,483 | 0.93% | 680 | 16 | City |
| Excelsior Springs | 7 | 10,630 | 10,584 | 0.08% | 980 | 11 | City |
| Parkville | 8 | 9,782 | 7,474 | 4.96% | 654 | 15 | City |
| North Kansas City | 9 | 6,178 | 4,568 | 5.5% | 1,413 | 4 | City |
| Pleasant Valley | 10 | 2,710 | 2,749 | -0.29% | 2,159 | 1 | City |
| Claycomo | 11 | 1,361 | 1,340 | 0.29% | 523 | 3 | Village |
| Lake Waukomis | 12 | 932 | 929 | 0.11% | 3,170 | 0 | City |
| Liberty | 13 | 888 | 850 | 1.25% | 27 | 33 | Township |
| Wood Heights | 14 | 755 | 752 | 0.13% | 331 | 2 | City |
| Glenaire | 15 | 527 | 537 | -0.38% | 1,945 | 0 | City |
| Holt | 16 | 471 | 473 | 0% | 908 | 1 | City |
| Avondale | 17 | 426 | 438 | -0.47% | 3,156 | 0 | City |
| Crystal Lakes | 18 | 395 | 397 | 0% | 359 | 1 | City |
| Platte Woods | 19 | 393 | 393 | 0% | 1,008 | 0 | City |
| Liberty | 20 | 369 | 367 | 0% | 11 | 35 | Township |
| Oakview | 21 | 359 | 368 | -0.55% | 2,051 | 0 | Village |
| Northmoor | 22 | 290 | 292 | 0% | 1,229 | 0 | City |
| Houston Lake | 23 | 224 | 223 | 0% | 1,867 | 0 | City |
| Missouri City | 24 | 218 | 217 | 0% | 199 | 1 | City |
| Oakwood | 25 | 194 | 199 | -0.51% | 985 | 0 | Village |
| Homestead | 26 | 192 | 192 | 0% | 1,208 | 0 | Village |
| Liberty | 27 | 192 | 194 | 0% | 4 | 48 | Township |
| Birmingham | 28 | 187 | 189 | 0% | 333 | 1 | Village |
| Oakwood Park | 29 | 184 | 186 | 0% | 2,746 | 0 | Village |
| Oaks | 30 | 126 | 128 | 0% | 1,385 | 0 | Village |
| Prathersville | 31 | 120 | 122 | 0% | 53 | 2 | Village |
| Grayson | 32 | 105 | 126 | 7.14% | 251 | 0 | CDP |
| Mosby | 33 | 98 | 100 | 0% | 53 | 2 | City |
| Randolph | 34 | 58 | 58 | 0% | 180 | 0 | Village |
Kansas City is the largest city in Clay County, with a population of 512,360.
Randolph is the smallest city in Clay County, with a population of 58.
There are 34 cities in Clay County, Missouri.