17 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Annual Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Kennett | 1 | 10,046 | 10,498 | -0.9% | 1,435 | 7 | City |
| Cotton Hill | 2 | 4,731 | 4,981 | -0.27% | 133 | 36 | Township |
| Malden | 3 | 3,481 | 3,700 | -1.25% | 418 | 8 | City |
| Senath | 4 | 1,495 | 1,587 | -1.25% | 777 | 2 | City |
| Campbell | 5 | 1,493 | 1,590 | -1.32% | 1,063 | 1 | City |
| Freeborn | 6 | 1,368 | 1,451 | -0.58% | 47 | 29 | Township |
| Holcomb | 7 | 1,259 | 1,333 | -0.63% | 31 | 40 | Township |
| Clay | 8 | 1,156 | 1,215 | -0.17% | 10 | 116 | Township |
| Clarkton | 9 | 937 | 1,004 | -1.47% | 830 | 1 | City |
| Holcomb | 10 | 585 | 627 | -1.52% | 1,003 | 1 | City |
| Cardwell | 11 | 527 | 562 | -1.31% | 837 | 1 | City |
| Hornersville | 12 | 498 | 533 | -1.39% | 638 | 1 | City |
| Arbyrd | 13 | 385 | 405 | -1.03% | 383 | 1 | City |
| Denton | 14 | 124 | 93 | 6.9% | 328 | 0 | CDP |
| Frisbee | 15 | 72 | 84 | 5.88% | 90 | 1 | CDP |
| White Oak | 16 | 64 | 150 | 6.67% | 508 | 0 | CDP |
| Rives | 17 | 42 | 42 | 0% | 115 | 0 | Town |
Kennett is the largest city in Dunklin County, with a population of 10,046.
Rives is the smallest city in Dunklin County, with a population of 42.
There are 17 cities in Dunklin County, Missouri.