9 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Annual Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Springfield | 1 | 170,862 | 169,177 | 0.2% | 2,053 | 83 | City |
| Republic | 2 | 20,975 | 18,897 | 2.02% | 1,309 | 16 | City |
| Willard | 3 | 6,622 | 6,369 | 0.78% | 1,095 | 6 | City |
| Strafford | 4 | 2,795 | 2,565 | 1.67% | 850 | 3 | City |
| Fair Grove | 5 | 1,625 | 1,585 | 0.49% | 510 | 3 | City |
| Ash Grove | 6 | 1,497 | 1,516 | -0.27% | 1,127 | 1 | City |
| Pleasant Hope | 7 | 696 | 668 | 0.87% | 458 | 2 | City |
| Walnut Grove | 8 | 634 | 648 | -0.47% | 1,021 | 1 | City |
| Springfield | 9 | 313 | 302 | 0.32% | 10 | 33 | Township |
Springfield is the largest city in Greene County, with a population of 170,862.
Springfield is the smallest city in Greene County, with a population of 313.
There are 9 cities in Greene County, Missouri.