12 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Annual Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Fayette | 1 | 2,841 | 2,798 | 0.32% | 1,281 | 2 | City |
| Fayette | 2 | 2,841 | 2,795 | 0.32% | 1,281 | 2 | City |
| Glasgow | 3 | 1,076 | 1,090 | -0.28% | 799 | 1 | City |
| Glasgow | 4 | 1,076 | 1,091 | -0.28% | 799 | 1 | City |
| New Franklin | 5 | 1,019 | 1,025 | -0.2% | 769 | 1 | City |
| New Franklin | 6 | 1,019 | 1,026 | -0.2% | 769 | 1 | City |
| Franklin | 7 | 460 | 465 | -0.43% | 14 | 32 | Township |
| Franklin | 8 | 460 | 463 | -0.43% | 14 | 32 | Township |
| Armstrong | 9 | 241 | 243 | -0.41% | 294 | 1 | City |
| Armstrong | 10 | 241 | 243 | -0.41% | 294 | 1 | City |
| Franklin | 11 | 70 | 68 | 0% | 303 | 0 | City |
| Franklin | 12 | 70 | 68 | 0% | 303 | 0 | City |
Fayette is the largest city in Howard County, with a population of 2,841.
Franklin is the smallest city in Howard County, with a population of 70.
There are 12 cities in Howard County, Missouri.