7 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Annual Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Ironton | 1 | 1,435 | 1,465 | -0.42% | 1,069 | 1 | City |
| Pilot Knob | 2 | 688 | 672 | 0.44% | 770 | 1 | City |
| Viburnum | 3 | 653 | 665 | -0.31% | 380 | 2 | City |
| Iron Mountain Lake | 4 | 648 | 642 | 0.15% | 330 | 2 | City |
| Arcadia | 5 | 602 | 617 | -0.5% | 728 | 1 | City |
| Annapolis | 6 | 244 | 248 | -0.41% | 652 | 0 | City |
| Des Arc | 7 | 128 | 130 | 0% | 604 | 0 | Village |
Ironton is the largest city in Iron County, with a population of 1,435.
Des Arc is the smallest city in Iron County, with a population of 128.
There are 7 cities in Iron County, Missouri.