22 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Annual Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Cobleskill | 1 | 6,379 | 6,091 | 0.05% | 208 | 31 | Town |
| Cobleskill | 2 | 4,602 | 4,257 | 1.52% | 1,291 | 4 | Village |
| Middleburgh | 3 | 3,150 | 3,114 | 0.16% | 64 | 49 | Town |
| Schoharie | 4 | 3,110 | 3,123 | -0.03% | 104 | 30 | Town |
| Richmondville | 5 | 2,467 | 2,473 | -0.08% | 82 | 30 | Town |
| Carlisle | 6 | 1,772 | 1,766 | 0.28% | 52 | 34 | Town |
| Sharon | 7 | 1,694 | 1,695 | 0.12% | 43 | 39 | Town |
| Seward | 8 | 1,591 | 1,590 | -0.19% | 44 | 36 | Town |
| Wright | 9 | 1,522 | 1,519 | 0.2% | 53 | 29 | Town |
| Jefferson | 10 | 1,346 | 1,333 | 0.07% | 31 | 43 | Town |
| Gilboa | 11 | 1,174 | 1,115 | 0.34% | 20 | 58 | Town |
| Middleburgh | 12 | 1,166 | 1,141 | 0.43% | 935 | 1 | Village |
| Summit | 13 | 1,071 | 1,070 | 0.09% | 29 | 37 | Town |
| Schoharie | 14 | 950 | 949 | 0% | 573 | 2 | Village |
| Richmondville | 15 | 872 | 877 | -0.11% | 472 | 2 | Village |
| Broome | 16 | 872 | 864 | 0.11% | 18 | 48 | Town |
| Conesville | 17 | 690 | 688 | 0% | 17 | 39 | Town |
| Central Bridge | 18 | 553 | 519 | -0.54% | 194 | 3 | CDP |
| Sharon Springs | 19 | 498 | 505 | -0.4% | 273 | 2 | Village |
| Blenheim | 20 | 317 | 312 | 0.63% | 9 | 34 | Town |
| Jefferson | 21 | 179 | 109 | 7.19% | 168 | 1 | CDP |
| North Blenheim | 22 | 99 | 27 | 7.61% | 219 | 0 | CDP |
Cobleskill is the largest city in Schoharie County, with a population of 6,379.
North Blenheim is the smallest city in Schoharie County, with a population of 99.
There are 22 cities in Schoharie County, New York.