11 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Annual Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Medford | 1 | 86,293 | 86,330 | -0.01% | 3,007 | 29 | City |
| Ashland | 2 | 20,829 | 21,356 | -0.51% | 3,139 | 7 | City |
| Central Point | 3 | 19,135 | 19,099 | 0.04% | 4,785 | 4 | City |
| Eagle Point | 4 | 9,834 | 9,719 | 0.23% | 3,313 | 3 | City |
| Talent | 5 | 6,304 | 6,311 | -0.03% | 4,740 | 1 | City |
| Phoenix | 6 | 4,590 | 4,490 | 0.44% | 2,404 | 2 | City |
| Shady Cove | 7 | 3,029 | 3,091 | -0.43% | 1,557 | 2 | City |
| Jacksonville | 8 | 2,925 | 3,025 | -0.68% | 1,546 | 2 | City |
| Rogue River | 9 | 2,317 | 2,417 | -0.86% | 2,401 | 1 | City |
| Gold Hill | 10 | 1,307 | 1,336 | -0.46% | 1,715 | 1 | City |
| Butte Falls | 11 | 430 | 442 | -0.69% | 1,005 | 0 | Town |
Medford is the largest city in Jackson County, with a population of 86,293.
Butte Falls is the smallest city in Jackson County, with a population of 430.
There are 11 cities in Jackson County, Oregon.