3 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Annual Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Hartsville-Trousdale County | 1 | 12,290 | 11,634 | 1.08% | 107 | 114 | Township |
| Lafayette | 2 | 6,002 | 5,587 | 1.4% | 1,133 | 5 | City |
| Red Boiling Springs | 3 | 1,215 | 1,208 | 0.08% | 694 | 2 | City |
Hartsville-Trousdale County is the largest city in Macon County, with a population of 12,290.
Red Boiling Springs is the smallest city in Macon County, with a population of 1,215.
There are 3 cities in Macon County, Tennessee.