3 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Annual Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Waynesboro | 1 | 2,310 | 2,314 | -0.04% | 539 | 4 | City |
| Clifton | 2 | 1,991 | 2,656 | -6.26% | 358 | 6 | City |
| Collinwood | 3 | 904 | 896 | 0.11% | 325 | 3 | City |
Waynesboro is the largest city in Wayne County, with a population of 2,310.
Collinwood is the smallest city in Wayne County, with a population of 904.
There are 3 cities in Wayne County, Tennessee.