52 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Annual Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Brownsville | 1 | 193,296 | 186,648 | 0.69% | 1,467 | 132 | City |
| Harlingen | 2 | 72,281 | 72,045 | 0.07% | 1,802 | 40 | City |
| San Benito | 3 | 24,679 | 24,843 | -0.13% | 1,562 | 16 | City |
| Los Fresnos | 4 | 8,663 | 8,160 | 1.17% | 1,986 | 4 | City |
| La Feria | 5 | 7,077 | 6,869 | 0.58% | 1,641 | 4 | City |
| Cameron Park | 6 | 5,547 | 5,716 | -1.67% | 10,178 | 1 | CDP |
| Primera | 7 | 5,491 | 5,278 | 0.77% | 1,977 | 3 | Town |
| Port Isabel | 8 | 5,257 | 5,020 | 0.9% | 775 | 7 | City |
| Laguna Vista | 9 | 3,854 | 3,538 | 1.66% | 798 | 5 | Town |
| Laureles | 10 | 3,850 | 4,046 | 0.29% | 802 | 5 | CDP |
| Combes | 11 | 3,286 | 3,151 | 0.83% | 1,012 | 3 | Town |
| Rancho Viejo | 12 | 2,871 | 2,830 | 0.28% | 1,399 | 2 | Town |
| La Paloma | 13 | 2,782 | 4,140 | -0.29% | 1,292 | 2 | CDP |
| Rio Hondo | 14 | 2,381 | 2,029 | 3.03% | 1,410 | 2 | City |
| Santa Rosa | 15 | 2,343 | 2,457 | -0.97% | 3,035 | 1 | Town |
| South Padre Island | 16 | 2,076 | 2,074 | 0% | 772 | 3 | Town |
| Encantada-Ranchito-El Calaboz | 17 | 2,015 | 1,832 | -0.79% | 766 | 3 | CDP |
| Rice Tracts | 18 | 1,481 | 540 | 7.16% | 792 | 2 | CDP |
| Palm Valley | 19 | 1,339 | 1,406 | -1.03% | 2,239 | 1 | City |
| Los Indios | 20 | 1,049 | 1,011 | 0.67% | 559 | 2 | Town |
| Laguna Heights | 21 | 980 | 1,778 | -14.63% | 6,087 | 0 | CDP |
| Reid Hope King | 22 | 961 | 1,008 | 1.26% | 3,337 | 0 | CDP |
| Indian Lake | 23 | 899 | 843 | 1.24% | 3,909 | 0 | Town |
| La Tina Ranch | 24 | 752 | 953 | 1.21% | 107 | 7 | CDP |
| Solis | 25 | 732 | 638 | 2.09% | 439 | 2 | CDP |
| Orason | 26 | 714 | 555 | 5.78% | 2,164 | 0 | CDP |
| Arroyo Colorado Estates | 27 | 706 | 670 | -2.62% | 654 | 1 | CDP |
| Olmito | 28 | 690 | 1,255 | -4.83% | 1,078 | 1 | CDP |
| Bluetown | 29 | 685 | 562 | 3.32% | 233 | 3 | CDP |
| Las Palmas II | 30 | 661 | 1,256 | -8.7% | 2,132 | 0 | CDP |
| Bayview | 31 | 575 | 475 | 3.6% | 148 | 4 | Town |
| Juarez | 32 | 565 | 1,787 | -5.04% | 2,825 | 0 | CDP |
| Santa Maria | 33 | 551 | 724 | -2.13% | 1,940 | 0 | CDP |
| South Point | 34 | 493 | 1,197 | -10.69% | 351 | 1 | CDP |
| Santa Rosa | 35 | 422 | 320 | 2.93% | 5,481 | 0 | CDP |
| Bixby | 36 | 408 | 604 | -1.45% | 260 | 2 | CDP |
| Villa Pancho | 37 | 368 | 378 | -7.07% | 1,252 | 0 | CDP |
| San Pedro | 38 | 317 | 182 | -4.52% | 261 | 1 | CDP |
| Arroyo Gardens | 39 | 281 | 198 | -4.1% | 71 | 4 | CDP |
| Zapata Ranch | 40 | 280 | 216 | 4.09% | 199 | 1 | CDP |
| Green Valley Farms | 41 | 267 | 409 | -20.06% | 69 | 4 | CDP |
| La Feria North | 42 | 251 | 233 | 1.21% | 220 | 1 | CDP |
| Los Fresnos | 43 | 246 | 24 | 6.96% | 1,359 | 0 | CDP |
| Villa Sol | 44 | 216 | 141 | 0.93% | 1,143 | 0 | CDP |
| Ratamosa | 45 | 107 | 99 | -7.76% | 53 | 2 | CDP |
| Lasana | 46 | 99 | 149 | 7.61% | 121 | 1 | CDP |
| Chula Vista | 47 | 79 | 135 | -15.05% | 432 | 0 | CDP |
| Del Mar Heights | 48 | 79 | 163 | -3.66% | 181 | 0 | CDP |
| Yznaga | 49 | 55 | 56 | 7.84% | 10 | 5 | CDP |
| Tierra Bonita | 50 | 45 | 65 | -11.76% | 50 | 1 | CDP |
| Iglesia Antigua | 51 | 12 | 212 | -68.42% | 6 | 2 | CDP |
| Santa Monica | 52 | 10 | 11 | 11.11% | 10 | 1 | CDP |
Brownsville is the largest city in Cameron County, with a population of 193,296.
Santa Monica is the smallest city in Cameron County, with a population of 10.
There are 52 cities in Cameron County, Texas.