9 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Annual Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Bay City | 1 | 17,326 | 18,048 | -0.83% | 1,869 | 9 | City |
| Palacios | 2 | 4,366 | 4,401 | -0.16% | 800 | 5 | City |
| Sargent | 3 | 1,550 | 1,204 | 7.12% | 208 | 7 | CDP |
| Markham | 4 | 1,257 | 1,029 | 0.96% | 559 | 2 | CDP |
| Van Vleck | 5 | 850 | 1,293 | -7.21% | 117 | 7 | CDP |
| Wadsworth | 6 | 447 | 428 | 6.94% | 60 | 7 | CDP |
| Matagorda | 7 | 353 | 519 | -2.75% | 191 | 2 | CDP |
| Blessing | 8 | 190 | 482 | -20.5% | 94 | 2 | CDP |
| Midfield | 9 | 16 | 231 | 6.67% | 35 | 0 | CDP |
Bay City is the largest city in Matagorda County, with a population of 17,326.
Midfield is the smallest city in Matagorda County, with a population of 16.
There are 9 cities in Matagorda County, Texas.