6 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Annual Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Raymondville | 1 | 10,079 | 10,218 | -0.28% | 2,449 | 4 | City |
| Lyford | 2 | 2,197 | 2,257 | -0.54% | 1,258 | 2 | City |
| Sebastian | 3 | 1,116 | 1,508 | -4.53% | 669 | 2 | CDP |
| Lasara | 4 | 1,072 | 787 | 0.28% | 742 | 1 | CDP |
| San Perlita | 5 | 545 | 533 | 0.37% | 1,050 | 1 | City |
| Port Mansfield | 6 | 79 | 127 | -10.23% | 16 | 5 | CDP |
Raymondville is the largest city in Willacy County, with a population of 10,079.
Port Mansfield is the smallest city in Willacy County, with a population of 79.
There are 6 cities in Willacy County, Texas.