6 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Annual Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Independence | 1 | 997 | 1,005 | -0.1% | 426 | 2 | Town |
| Independence | 2 | 997 | 1,002 | -0.1% | 426 | 2 | Town |
| Fries | 3 | 442 | 451 | -0.45% | 693 | 1 | Town |
| Fries | 4 | 442 | 449 | -0.45% | 693 | 1 | Town |
| Troutdale | 5 | 139 | 140 | 0% | 44 | 3 | Town |
| Troutdale | 6 | 139 | 139 | 0% | 44 | 3 | Town |
Independence is the largest city in Grayson County, with a population of 997.
Troutdale is the smallest city in Grayson County, with a population of 139.
There are 6 cities in Grayson County, Virginia.