San Acacio
- County:
- Conejos County
- County Seat:
- No
- Area (mi²):
- 1.257
- State:
- Colorado
San Acacio is a CDP located in Conejos County, Colorado. San Acacio has a 2025 population of 71. San Acacio is currently growing at a rate of 7.58% annually but its population has decreased by -47.41% since the most recent census, which recorded a population of 135 in 2020.
The median age in San Acacio is 74.5 years: 0 years for males, and 0 years for females.