17 cities
| City | County | 2025 Pop. ↓ |
|---|---|---|
| D'Iberville | Harrison County | 13,569 |
| Diamondhead | Hancock County | 9,361 |
| Durant | Holmes County | 1,916 |
| Decatur | Newton County | 1,872 |
| DeLisle | Hancock County | 1,692 |
| Drew | Sunflower County | 1,639 |
| Duck Hill | Montgomery County | 1,471 |
| Derma | Calhoun County | 911 |
| De Kalb | Kemper County | 821 |
| Dumas | Tippah County | 458 |
| D'Lo | Rankin County | 363 |
| De Soto | Clarke County | 341 |
| Duncan | Bolivar County | 263 |
| Darling | Quitman County | 140 |
| Doddsville | Sunflower County | 65 |
| Dundee | Tunica County | 56 |
| Dennis | Tishomingo County | 26 |