3 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Annual Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Carthage | 1 | 4,846 | 4,891 | -0.19% | 521 | 9 | City |
| Walnut Grove | 2 | 508 | 507 | 0% | 314 | 2 | Town |
| Lena | 3 | 156 | 160 | -0.64% | 94 | 2 | Town |
Carthage is the largest city in Leake County, with a population of 4,846.
Lena is the smallest city in Leake County, with a population of 156.
There are 3 cities in Leake County, Mississippi.