Lisco
- County:
- Garden County
- County Seat:
- No
- Area (mi²):
- 0.595
- State:
- Nebraska
Lisco is a CDP located in Garden County, Nebraska. Lisco has a 2025 population of 20. Lisco is currently growing at a rate of 5.26% annually but its population has decreased by -47.37% since the most recent census, which recorded a population of 38 in 2020.
The median age in Lisco is 86.3 years: 0 years for males, and 0 years for females.