Oswego
- County:
- Lee County
- County Seat:
- No
- Area (mi²):
- 1.205
- State:
- South Carolina
Oswego is a CDP located in Lee County, South Carolina. Oswego has a 2025 population of 440. Oswego is currently growing at a rate of 7.06% annually and its population has increased by 123.35% since the most recent census, which recorded a population of 197 in 2020.
The median age in Oswego is 15.4 years: 0 years for males, and 13.5 years for females.