Cuenca's 2025 population is now estimated at 461,143. In 1950, the population of Cuenca was 39,418. Cuenca has grown by 8,151 in the last year, which represents a 1.8% annual change. These population estimates and projections come from the latest revision of the UN World Urbanization Prospects . These estimates represent the Urban agglomeration of Cuenca, which typically includes Cuenca's population in addition to adjacent suburban areas.
| City | 2025 Pop. ↓ | Growth |
|---|---|---|
| Guayaquil | 3,244,750 | |
| Quito | 2,017,260 | |
| Santo Domingo de los Colorados | 200,421 | |
| Eloy Alfaro | 167,784 | |
| Machala | 144,197 | |
| Tutamandahostel | 140,000 | |
| Portoviejo | 132,937 | |
| Manta | 125,505 | |
| Ambato | 124,166 | |
| Loja | 94,300 | |
| Tulcan | 86,498 | |
| Velasco Ibarra | 48,754 | |
| Puerto Francisco de Orellana | 48,144 | |
| Ventanas | 46,708 | |
| Pasaje | 44,860 | |
| Chone | 44,751 | |
| Salinas | 43,862 | |
| Santa Elena | 42,214 | |
| Rosa Zarate | 42,121 | |
| Santa Rosa | 41,816 | |
| Balzar | 40,115 | |
| Huaquillas | 39,757 | |
| Bahia de Caraquez | 37,056 | |
| La Troncal | 36,353 | |
| Jipijapa | 35,901 | |
| Azogues | 34,877 | |
| Naranjito | 34,206 | |
| Vinces | 32,497 | |
| Otavalo | 32,330 | |
| El Triunfo | 32,282 | |
| Naranjal | 32,045 | |
| Playas | 30,564 | |
| Yaguachi Nuevo | 27,947 | |
| Cayambe | 26,582 | |
| Machachi | 25,742 | |
| Puyo | 24,881 | |
| Nueva Loja | 24,211 | |
| Samborondon | 24,118 | |
| Macas | 23,687 | |
| Pedro Carbo | 23,372 | |
| Guaranda | 22,199 | |
| Boca Suno | 20,313 | |
| San Lorenzo de Esmeraldas | 20,209 | |
| Catamayo | 18,565 | |
| Montecristi | 18,351 | |
| Atuntaqui | 17,456 | |
| Calceta | 17,286 | |
| Tena | 17,172 | |
| Gualaceo | 17,122 | |
| Pinas | 16,981 | |
| Cariamanga | 16,862 | |
| Pelileo | 16,572 | |
| La Mana | 16,450 | |
| Pujili | 16,168 | |
| Montalvo | 15,547 | |
| Sucre | 15,286 | |
| Zamora | 15,276 | |
| San Gabriel | 15,112 | |
| Tosagua | 14,680 | |
| Alausi | 14,294 | |
| Muisne | 13,393 | |
| Macara | 13,035 | |
| Santa Ana | 12,833 | |
| Guano | 12,659 | |
| Alfredo Baquerizo Moreno | 12,617 | |
| San Miguel | 12,575 | |
| Santa Lucia | 12,523 | |
| Zaruma | 12,505 | |
| Balao | 12,205 | |
| Valdez | 11,441 | |
| Catacocha | 10,872 | |
| San Miguel de Salcedo | 10,838 | |
| Rocafuerte | 10,274 |