Grand-Santi's 2026 population is now estimated at 10,318. In 2006, the population of Grand-Santi was 3,351. Grand-Santi has grown by 221 in the last year, which represents a 2.19% annual change. These population values and projections come from INSEE historical municipal populations (French Guiana communes, PMUN) and World Population Review Internal Projections .
| City | 2026 Pop. ↓ | Growth |
|---|---|---|
| Cayenne | 61,678 | -0.53% |
| Saint-Laurent-du-Maroni | 60,107 | 3.36% |
| Matoury | 38,790 | 2.04% |
| Remire-Montjoly | 28,753 | 1.23% |
| Kourou | 24,638 | -0.25% |
| Macouria | 22,918 | 4.82% |
| Apatou | 10,917 | 1.94% |
| Mana | 10,778 | -0.54% |
| Grand-Santi | 10,318 | 2.19% |
| Maripasoula | 7,927 | -6.11% |
| Saint-Georges | 5,428 | 3.37% |
| Papaichton | 4,511 | -3.43% |
| Montsinéry-Tonnegrande | 4,252 | 5.46% |
| Roura | 3,452 | 0.03% |
| Régina | 2,752 | 18.42% |
| Sinnamary | 2,678 | -0.96% |
| Camopi | 2,481 | 4.24% |
| Awala-Yalimapo | 1,676 | 2.07% |
| Iracoubo | 1,600 | -1.23% |
| Saül | 452 | 17.71% |
| Saint-Élie | 124 | -8.15% |
| Ouanary | 121 | -6.92% |