Penonome's 2026 population is now estimated at 19,704. In 2000, the population of Penonome was 11,447. Penonome has grown by 236 in the last year, which represents a 1.21% annual change. These population values and projections come from Panama census 2000 nomenclature places, Panama census 2010 nomenclature places, Panama census 2023 Cuadro 3 place population and World Population Review Internal Projections .