San Francisco
- Country:
- Panama
- Continent:
- North America
San Francisco's 2026 population is now estimated at 24,374. In 2000, the population of San Francisco was 35,751. San Francisco experienced a decrease of -914 residents over the past year, marking an annual decline of -3.61%. These population values and projections come from Panama census 2000 nomenclature places, Panama census 2010 nomenclature places, Panama census 2023 Cuadro 3 place population and World Population Review Internal Projections .