Ciudad del Este's 2025 population is now estimated at 344,919. In 1950, the population of Ciudad del Este was 193. Ciudad del Este has grown by 5,009 in the last year, which represents a 1.47% annual change. These population estimates and projections come from the latest revision of the UN World Urbanization Prospects . These estimates represent the Urban agglomeration of Ciudad del Este, which typically includes Ciudad del Este's population in addition to adjacent suburban areas.
| City | 2025 Pop. ↓ | Growth |
|---|---|---|
| Asuncion | 3,627,220 | |
| San Lorenzo | 133,395 | |
| Lambare | 99,572 | |
| Fernando de la Mora | 95,072 | |
| Capiata | 83,773 | |
| Encarnacion | 56,261 | |
| Pedro Juan Caballero | 53,566 | |
| Mariano Roque Alonso | 39,289 | |
| Coronel Oviedo | 38,316 | |
| Caaguazu | 38,220 | |
| Concepcion | 35,276 | |
| Presidente Franco | 31,825 | |
| Villa Elisa | 29,796 | |
| Villarrica | 27,818 | |
| Nemby | 26,999 | |
| Limpio | 26,177 | |
| Caazapa | 23,996 | |
| Pilar | 19,121 | |
| San Juan Bautista | 16,593 | |
| Ita | 14,259 | |
| Itaugua | 13,910 | |
| Nueva Esperanza | 12,717 | |
| Caacupe | 12,382 | |
| Juan de Ayolas | 12,061 | |
| Villa Hayes | 11,859 | |
| Santa Rita | 11,823 | |
| Colonia General Alfredo Stroessner | 11,558 | |
| San Isidro de Curuguaty | 11,095 | |
| Horqueta | 10,531 | |
| Lima | 10,367 | |
| Piribebuy | 10,337 | |
| Paraguari | 10,079 |