34 cities
| City | County | 2025 Pop. ↓ |
|---|---|---|
| Clinton | Hinds County | 26,279 |
| Columbus | Lowndes County | 22,526 |
| Corinth | Alcorn County | 14,121 |
| Clarksdale | Coahoma County | 13,632 |
| Canton | Madison County | 10,743 |
| Cleveland | Bolivar County | 9,942 |
| Columbia | Marion County | 6,476 |
| Carthage | Leake County | 4,846 |
| Crystal Springs | Copiah County | 4,626 |
| Collins | Covington County | 2,217 |
| Cleary | Rankin County | 2,127 |
| Collinsville | Lauderdale County | 1,742 |
| Charleston | Tallahatchie County | 1,652 |
| Calhoun City | Calhoun County | 1,462 |
| Columbus AFB | Lowndes County | 1,442 |
| Coldwater | Tate County | 1,311 |
| Conehatta | Newton County | 1,214 |
| Caledonia | Monroe County | 1,112 |
| Centreville | Wilkinson County | 1,097 |
| Como | Panola County | 1,063 |
| Coffeeville | Yalobusha County | 774 |
| Clara | Wayne County | 644 |
| Crenshaw | Panola County | 611 |
| Cloverdale | Adams County | 550 |
| Crowder | Quitman County | 525 |
| Courtland | Panola County | 478 |
| Carrollton | Carroll County | 408 |
| Crawford | Lowndes County | 407 |
| Chunky | Newton County | 267 |
| Cruger | Holmes County | 237 |
| Cary | Sharkey County | 221 |
| Coahoma | Coahoma County | 215 |
| Crosby | Amite County | 215 |
| Chalybeate | Alcorn County | 14 |