17 cities
| City | County | 2025 Pop. ↓ |
|---|---|---|
| North Charleston | Berkeley County | 128,603 |
| North Augusta | Aiken County | 26,872 |
| North Myrtle Beach | Horry County | 21,266 |
| Newberry | Newberry County | 10,918 |
| Newport | York County | 4,248 |
| Northlake | Anderson County | 4,050 |
| North Hartsville | Chesterfield County | 3,264 |
| New Ellenton | Aiken County | 2,388 |
| Ninety Six | Greenwood County | 2,075 |
| Newtown | Dillon County | 961 |
| Norris | Pickens County | 755 |
| North | Orangeburg County | 673 |
| North Santee | Clarendon County | 588 |
| Newry | Oconee County | 383 |
| Neeses | Orangeburg County | 314 |
| Norway | Orangeburg County | 273 |
| Nichols | Horry County | 218 |