51 cities
| City | State | 2025 Pop. ↓ | Annual Change | Rank | Type |
|---|---|---|---|---|---|
| Boston | Massachusetts | 682,313 | 1.31% | 1 | City |
| Worcester | Massachusetts | 213,361 | 0.98% | 2 | City |
| Providence | Rhode Island | 195,681 | 0.5% | 3 | City |
| Springfield | Massachusetts | 155,556 | 0.43% | 4 | City |
| Bridgeport | Connecticut | 152,570 | 0.64% | 5 | City |
| Stamford | Connecticut | 140,049 | 0.66% | 6 | City |
| New Haven | Connecticut | 139,624 | 1.5% | 7 | City |
| Cambridge | Massachusetts | 123,057 | 1.54% | 8 | City |
| Hartford | Connecticut | 122,544 | 0.34% | 9 | City |
| Lowell | Massachusetts | 121,683 | 1.05% | 10 | City |
| Manchester | New Hampshire | 117,080 | 0.6% | 11 | City |
| Waterbury | Connecticut | 116,412 | 0.43% | 12 | City |
| Brockton | Massachusetts | 106,340 | 0.52% | 13 | City |
| Lynn | Massachusetts | 105,110 | 1.57% | 14 | City |
| Quincy | Massachusetts | 104,564 | 1.09% | 15 | City |
| New Bedford | Massachusetts | 101,629 | 0.31% | 16 | City |
| Fall River | Massachusetts | 95,083 | 0.42% | 17 | City |
| Norwalk | Connecticut | 94,352 | 0.74% | 18 | City |
| Nashua | New Hampshire | 92,574 | 0.79% | 19 | City |
| Newton | Massachusetts | 92,139 | 1.59% | 20 | City |
| Lawrence | Massachusetts | 89,915 | 0.65% | 21 | City |
| Danbury | Connecticut | 89,341 | 0.73% | 22 | City |
| Cranston | Rhode Island | 84,867 | 0.5% | 23 | City |
| Warwick | Rhode Island | 83,727 | 0.21% | 24 | City |
| Somerville | Massachusetts | 83,058 | 1.11% | 25 | City |
| Pawtucket | Rhode Island | 77,373 | 0.49% | 26 | City |
| New Britain | Connecticut | 76,603 | 0.96% | 27 | City |
| Framingham | Massachusetts | 74,098 | 1% | 28 | City |
| Portland | Maine | 69,769 | 0.29% | 29 | City |
| Haverhill | Massachusetts | 68,739 | 0.66% | 30 | City |
| Plymouth | Massachusetts | 67,626 | 1.44% | 31 | Town |
| Malden | Massachusetts | 67,546 | 1.28% | 32 | City |
| Waltham | Massachusetts | 66,533 | 1.04% | 33 | City |
| Fairfield | Connecticut | 66,385 | 1.66% | 34 | Township |
| Greenwich | Connecticut | 65,196 | 0.93% | 35 | Township |
| Brookline | Massachusetts | 64,662 | 1.15% | 36 | Town |
| West Hartford | Connecticut | 64,462 | 0.43% | 37 | Township |
| Taunton | Massachusetts | 62,793 | 1.38% | 38 | City |
| Bristol | Connecticut | 62,557 | 0.58% | 39 | City |
| Revere | Massachusetts | 62,438 | 2.86% | 40 | City |
| Hamden | Connecticut | 61,609 | 0.16% | 41 | Township |
| Meriden | Connecticut | 60,905 | 0.09% | 42 | City |
| Weymouth Town | Massachusetts | 60,775 | 1.02% | 43 | City |
| Medford | Massachusetts | 60,401 | 0.84% | 44 | City |
| Manchester | Connecticut | 60,201 | 0.42% | 45 | Township |
| Peabody | Massachusetts | 55,793 | 0.68% | 46 | City |
| Chicopee | Massachusetts | 55,415 | 0.06% | 47 | City |
| West Haven | Connecticut | 55,335 | -0.08% | 48 | City |
| Stratford | Connecticut | 54,272 | 1.23% | 49 | Township |
| Everett | Massachusetts | 52,802 | 1.89% | 50 | City |
| East Hartford | Connecticut | 51,323 | 0.38% | 51 | Township |
For this list, the New England Region is defined as the 6 states of Connecticut, Maine, Massachusetts, New Hampshire, Rhode Island and Vermont.