26 cities
| City | Rank | County | 2025 Pop. ↓ |
|---|---|---|---|
| Richmond | 1 | Madison County | 40,652 |
| Nicholasville | 2 | Jessamine County | 34,039 |
| Danville | 3 | Boyle County | 17,622 |
| Berea | 4 | Madison County | 16,645 |
| Campbellsville | 5 | Taylor County | 11,916 |
| Harrodsburg | 6 | Mercer County | 9,570 |
| Lebanon | 7 | Marion County | 6,624 |
| Wilmore | 8 | Jessamine County | 6,333 |
| Lancaster | 9 | Garrard County | 4,127 |
| Stanford | 10 | Lincoln County | 3,715 |
| Stanton | 11 | Powell County | 3,152 |
| Junction City | 12 | Boyle County | 2,342 |
| Irvine | 13 | Estill County | 2,269 |
| Clay City | 14 | Powell County | 1,172 |
| Burgin | 15 | Mercer County | 1,025 |
| McKee | 16 | Estill County | 833 |
| Perryville | 17 | Boyle County | 806 |
| Crab Orchard | 18 | Lincoln County | 760 |
| Loretto | 19 | Marion County | 708 |
| Ravenna | 20 | Estill County | 551 |
| Hustonville | 21 | Lincoln County | 398 |
| Bradfordsville | 22 | Marion County | 274 |
| Salvisa | 23 | Mercer County | 218 |
| Raywick | 24 | Marion County | 154 |
| St. Mary | 25 | Marion County | 140 |
| Keene | 26 | Jessamine County | 107 |
Madison County, Jessamine County, Boyle County, Taylor County, Lincoln County, Mercer County, Marion County, Garrard County, Estill County, and Powell County are the counties generally considered part of Central Kentucky.