South Illinois Cities

117 cities

City
Rank
County
2025 Pop. ↓
Carbondale1Jackson County22,213
Marion2Williamson County17,068
Mount Vernon3Jefferson County14,060
Herrin4Williamson County12,230
Harrisburg5Saline County7,858
West Frankfort6Franklin County7,099
Murphysboro7Jackson County7,035
Benton8Franklin County6,547
Carterville9Williamson County5,812
Metropolis10Massac County5,731
Du Quoin11Perry County5,561
Pinckneyville12Perry County4,937
Fairfield13Wayne County4,765
Anna14Union County4,135
Eldorado15Saline County3,545
Johnston City16Williamson County3,291
Christopher17Franklin County2,605
McLeansboro18Franklin County2,578
Sesser19Franklin County1,871
Cambria20Williamson County1,853
Ina21Jefferson County1,647
Jonesboro22Union County1,642
Carrier Mills23Saline County1,584
Crainville24Jackson County1,505
Cairo25Alexander County1,474
Zeigler26Franklin County1,461
De Soto27Jackson County1,408
Vienna28Johnson County1,349
Goreville29Johnson County1,051
Royalton30Franklin County1,037
Cobden31Union County1,032
Wayne City32Wayne County989
Harrison33Jackson County975
Energy34Williamson County953
Rosiclare35Hardin County946
Elkville36Jackson County833
Galatia37Saline County778
Hurst38Williamson County748
Brookport39Massac County683
Dongola40Union County641
West City41Franklin County636
Cisne42Wayne County620
Golconda43Pope County619
Woodlawn44Jefferson County603
Bluford45Jefferson County599
Mounds46Pulaski County596
Pittsburg47Williamson County559
Willisville48Perry County554
Ava49Jackson County546
Makanda50Jackson County539
Valier51Franklin County535
Tamaroa52Perry County523
Olive Branch53Alexander County506
Creal Springs54Williamson County496
North City55Franklin County496
Dahlgren56Hamilton County490
Thompsonville57Franklin County477
Grand Tower58Jackson County474
Mound City59Pulaski County471
Ullin60Pulaski County455
Dix61Jefferson County453
Waltonville62Jefferson County398
Karnak63Pulaski County397
Buckner64Franklin County395
Dowell65Jackson County367
Bonnie66Jefferson County362
Tamms67Alexander County361
Cutler68Perry County352
Blairsville69Jackson County350
Jeffersonville70Wayne County348
Joppa71Massac County328
Orient72Franklin County319
Hanaford73Franklin County313
Campbell Hill74Jackson County307
Alto Pass75Union County303
Belle Rive76Jefferson County298
Ewing77Franklin County294
Raleigh78Saline County275
Freeman Spur79Williamson County270
Olmsted80Pulaski County262
Opdyke81Jefferson County260
East Cape Girardeau82Alexander County244
Crab Orchard83Williamson County241
Bush84Jackson County236
Vergennes85Jackson County236
Whiteash86Williamson County236
Elizabethtown87Hardin County221
Cave-In-Rock88Hardin County219
Cypress89Johnson County219
Stonefort90Saline County218
McClure91Alexander County217
Buncombe92Johnson County207
Nason93Jefferson County195
Broughton94Hamilton County178
Spillertown95Williamson County176
Thebes96Alexander County176
Colp97Williamson County174
Gorham98Jackson County171
Sims99Wayne County168
New Minden100Perry County162
St. Johns101Jackson County155
New Burnside102Johnson County152
New Grand Chain103Massac County143
Pulaski104Pulaski County140
Eddyville105Pope County96
Mount Erie106Wayne County94
Belknap107Johnson County86
Johnsonville108Wayne County70
Unity109Alexander County68
Golden Gate110Wayne County61
Muddy111Saline County56
Mill Creek112Pulaski County55
Mulkeytown113Franklin County55
Keenes114Wayne County49
Belle Prairie City115Hamilton County45
Simpson116Johnson County44
Macedonia117Hamilton County29

About South Illinois

Sources

  1. City and Town Population Totals: 2020-2024