| County | Rank | Change (2020) ↓ | 2025 Pop. | 2020 Pop. |
|---|---|---|---|---|
| Stone County | 1 | 9.85% | 20,134 | 18,329 |
| Lafayette County | 2 | 7.82% | 60,286 | 55,916 |
| George County | 3 | 7.4% | 26,171 | 24,367 |
| Pearl River County | 4 | 6.5% | 59,862 | 56,207 |
| DeSoto County | 5 | 6.26% | 197,781 | 186,129 |
| Madison County | 6 | 5.65% | 115,426 | 109,252 |
| Lamar County | 7 | 4.45% | 67,261 | 64,393 |
| Harrison County | 8 | 3.46% | 216,066 | 208,835 |
| Pontotoc County | 9 | 3.44% | 32,267 | 31,195 |
| Jackson County | 10 | 3.11% | 147,839 | 143,378 |
| Prentiss County | 11 | 2.78% | 25,668 | 24,974 |
| Rankin County | 12 | 2.41% | 160,962 | 157,175 |
| Marshall County | 13 | 2.32% | 34,568 | 33,783 |
| Union County | 14 | 2.29% | 28,451 | 27,814 |
| Tate County | 15 | 2.11% | 28,713 | 28,119 |
| Webster County | 16 | 1.87% | 10,089 | 9,904 |
| Itawamba County | 17 | 1.64% | 24,257 | 23,865 |
| Leake County | 18 | 1.59% | 21,588 | 21,250 |
| Hancock County | 19 | 1.5% | 46,823 | 46,130 |
| Greene County | 20 | 1.45% | 13,725 | 13,529 |
| Oktibbeha County | 21 | 0.97% | 52,209 | 51,705 |
| Yalobusha County | 22 | 0.89% | 12,547 | 12,436 |
| Lincoln County | 23 | 0.73% | 35,097 | 34,844 |
| Forrest County | 24 | 0.29% | 78,438 | 78,212 |
| Neshoba County | 25 | 0.12% | 29,038 | 29,003 |
| Walthall County | 26 | -0.22% | 13,843 | 13,873 |
| Lee County | 27 | -0.23% | 83,131 | 83,319 |
| Wayne County | 28 | -0.26% | 19,755 | 19,807 |
| Benton County | 29 | -0.37% | 7,641 | 7,669 |
| Perry County | 30 | -0.7% | 11,379 | 11,459 |
| Newton County | 31 | -0.8% | 21,085 | 21,254 |
| Panola County | 32 | -0.88% | 32,877 | 33,170 |
| Alcorn County | 33 | -0.93% | 34,410 | 34,732 |
| Scott County | 34 | -0.94% | 27,713 | 27,977 |
| Issaquena County | 35 | -1.13% | 1,310 | 1,325 |
| Choctaw County | 36 | -1.18% | 8,110 | 8,207 |
| Tippah County | 37 | -1.23% | 21,469 | 21,737 |
| Simpson County | 38 | -1.35% | 25,541 | 25,890 |
| Jefferson Davis County | 39 | -1.36% | 11,121 | 11,274 |
| Tishomingo County | 40 | -1.44% | 18,582 | 18,854 |
| Smith County | 41 | -1.49% | 13,994 | 14,205 |
| Covington County | 42 | -1.59% | 18,010 | 18,301 |
| Winston County | 43 | -1.84% | 17,360 | 17,686 |
| Marion County | 44 | -2.02% | 23,883 | 24,376 |
| Amite County | 45 | -2.16% | 12,428 | 12,702 |
| Chickasaw County | 46 | -2.18% | 16,710 | 17,083 |
| Monroe County | 47 | -2.36% | 33,330 | 34,135 |
| Jones County | 48 | -2.44% | 65,533 | 67,173 |
| Clay County | 49 | -2.47% | 18,161 | 18,621 |
| Lowndes County | 50 | -2.95% | 57,051 | 58,783 |
| Lawrence County | 51 | -2.99% | 11,626 | 11,984 |
| Clarke County | 52 | -3.07% | 15,070 | 15,547 |
| Adams County | 53 | -3.17% | 28,494 | 29,427 |
| Lauderdale County | 54 | -3.3% | 70,275 | 72,676 |
| Copiah County | 55 | -3.31% | 27,335 | 28,271 |
| Franklin County | 56 | -3.33% | 7,406 | 7,661 |
| Calhoun County | 57 | -3.59% | 12,742 | 13,216 |
| Pike County | 58 | -3.74% | 38,689 | 40,193 |
| Grenada County | 59 | -3.79% | 20,759 | 21,577 |
| Attala County | 60 | -4.04% | 17,098 | 17,817 |
| Jasper County | 61 | -4.43% | 15,628 | 16,352 |
| Noxubee County | 62 | -5.03% | 9,712 | 10,226 |
| Kemper County | 63 | -5.11% | 8,504 | 8,962 |
| Montgomery County | 64 | -5.47% | 9,257 | 9,793 |
| Jefferson County | 65 | -5.78% | 6,826 | 7,245 |
| Warren County | 66 | -5.98% | 41,887 | 44,550 |
| Coahoma County | 67 | -5.99% | 19,957 | 21,228 |
| Carroll County | 68 | -7.2% | 9,224 | 9,940 |
| Hinds County | 69 | -7.65% | 209,433 | 226,772 |
| Tunica County | 70 | -8.22% | 8,934 | 9,734 |
| Humphreys County | 71 | -9.18% | 7,025 | 7,735 |
| Leflore County | 72 | -9.25% | 25,719 | 28,341 |
| Washington County | 73 | -9.38% | 40,460 | 44,648 |
| Bolivar County | 74 | -9.41% | 27,940 | 30,843 |
| Holmes County | 75 | -9.43% | 15,284 | 16,876 |
| Wilkinson County | 76 | -10.23% | 7,652 | 8,524 |
| Quitman County | 77 | -10.74% | 5,492 | 6,153 |
| Sunflower County | 78 | -13.94% | 22,118 | 25,702 |
| Claiborne County | 79 | -14.04% | 7,819 | 9,096 |
| Sharkey County | 80 | -18.12% | 3,090 | 3,774 |
| Tallahatchie County | 81 | -18.36% | 10,325 | 12,647 |
| Yazoo County | 82 | -19.59% | 21,445 | 26,670 |
Mississippi's counties show varied growth patterns from 2020 to 2025. Stone County leads with 9.85% annualized growth, followed by Lafayette County (7.82%) and George County (7.4%). The largest counties are Harrison County (216,066), Hinds County (209,433), and DeSoto County (197,781). Of the 82 counties in Mississippi, 25 are growing while 57 have experienced population decline. Overall, counties averaged -2.44% annualized growth, with total population growing by -0.53% annually.
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