11 zips
| Zip Code | City | Population ↓ |
|---|---|---|
| 63701 | Cape Girardeau | 38,809 |
| 63755 | Jackson | 27,378 |
| 63703 | Cape Girardeau | 8,494 |
| 63766 | Millersville | 1,830 |
| 63769 | Oak Ridge | 1,388 |
| 63785 | Whitewater | 1,071 |
| 63747 | Friedheim | 698 |
| 63739 | Burfordville | 577 |
| 63744 | Delta | 177 |
| 63745 | Dutchtown | 146 |
| 63743 | Daisy | 20 |
The data shown reflect ZCTAs from the US Census. As of 2024, there are 11 ZCTAs in Cape Girardeau County, Missouri (US Census).